Much of the literature about globalization exaggerates the degree of novelty. In this review, we concentrate on claims about what has changed about cities under late capitalism and globalization. Although we suggest that cities have long been influenced by global forces, we conclude that the roles of cities in the global system have changed considerably as a result of the time-space compression made possible by new transportation, communication, and organizational technologies. After discussing what the global perspective means within anthropology, and how it affects urban anthropological research, our review concentrates on three complex issues. First is whether the global factory and increasing knowledge-intensivity have decreased or increased the utility of the intermediary or brokerage roles that cities play. Second, we examine changes in how people live in globalizing cities. Third, we consider the implications of the construction and maintenance of relationships across borders for processes of citizenship, affiliation, and transnational social movements.