Models of Survival in HIV Infection and their Use in the Quantification of Treatment Benefits
Author(s)
Veugelers, Paul J.; Cornelisse, Peter G. A.; Craib, Kevin J. P.; Marion, Steven A.; Hogg, Robert S.; Strathdee, Steffanie A.; Montaner, Julio, S. G.; O’Shaughnessy, Michael V.; Schechter, Martin T.
Abstract
Sufficient follow-up data are available to allow modeling of survival time for AIDS patients. Nonparametric and parametric models of mortality have been evaluated using data from 554 seropositive participants in the Vancouver Lymphadenophathy-AIDS Study. Pronounced treatment benefits at the national level have been noted. Mortality rates leveled off in the mid-1990s. Availability of treatment in Canada and shape of the historical HIV infection curve were factors.
