Anthropological Genetics in the Genomic Era: A Look Back and Ahead
Author(s)
O’Rourke, Dennis H.
Abstract
The use of genetic methods and data has a long history in anthropology. Following dramatic growth in anthropological genetic field studies in the 1960s and 1970s, the revolution in molecular genetic methods during the 1980s spurred another period of growth and expansion. The earlier emphasis on examination of the role of alternative evolutionary mechanisms in structuring allele frequency variation within and between populations is reflected today in a renewed focus on unraveling demographic history using highly informative molecular markers. The existence of large, publicly available molecular genetic databases, coupled with advances in analytical methods, makes it possible to tackle a wide variety of problems in human evolution not possible with classical markers and traditional analytical methods. These recent advances will help frame the nature of research in the discipline in the near term.