Inge Kaul suggests that the policy attention accorded to health concerns today is due to a growing mismatch between the nature of the health challenges which the international community is facing and that of the response options typically available in the ‘tool-kit’ of present-day policy-makers. The former are increasingly global, and the latter are still predominantly national, and sometimes even increasingly sub-national. As a result, many health issues today fall between the ‘cracks’ of policy-making and remain unresolved.